Go to this page to design your custom TALENS.
Go to this page to design your custom CRISPR guide RNAs.
E-TALEN is a software tool to design and evaluate Transcription Activator Like Effector Nucleases (TALEN)

E-TALEN is a web service to design TALENs for introducing knock-out mutations, for endogenous tagging and targeted excision repair. The tool can be used to design TALENs against a single target but also for up to 50 target genes in parallel. E-TALEN guides the user through end-to-end de-novo design process for specific sequences or genomic loci. In addition, it can also be used to evaluate existing TALEN designs.

UPDATE: E-TALEN now offers improved functionality.

Boutros lab, E-TALEN-Version 2.5
For suggestions please contact us at crispr@dkfz.de